Acanthosis Nigricans

Acanthosis nigricans is a velvetly hyperpigmentation of the skin. It associates with Insulin resistance, endocrine disorders, obesity, drugs, and malignancy.

Etiology:
The etiology is unclear but may be related to the growth factors on skin

Signs and Symptoms:
Dark, thickened, dirty-appearing, velvety plaques predominantly in the flexural areas such as axillae, neck, and under the breast and groin

Treatments:
Treat the underlying disorder such as weight reduction for obesity and insulin resistance